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HBOT Therapy Benefits: How Hyperbaric Medicine Can Positively Impact Dozens of Conditions, Including Most Chronic Diseases

Written by Portland Clinic of Natural Health on June 8, 2023

Hyperbaric Oxygen Therapy (HBOT) has gained recognition as a potential treatment for various medical conditions. By delivering high levels of oxygen under increased atmospheric pressure, HBOT offers unique therapeutic benefits. In this blog post, we will explore the evidence-based benefits of HBOT across multiple conditions, including chronic diseases, and discuss how it can positively impact patient outcomes.

  1. Chronic Wound Healing

HBOT has demonstrated significant effectiveness in promoting wound healing, particularly in chronic and non-healing wounds. By increasing oxygen levels, HBOT stimulates the growth of new blood vessels, accelerates tissue repair, and enhances the body's natural healing processes. This therapy is especially beneficial for patients with conditions such as diabetic foot ulcers, venous ulcers, and pressure sores. (1)

  1. Diabetic Complications

Diabetes often leads to various complications, including peripheral neuropathy and diabetic foot ulcers. HBOT has shown promise in improving the outcomes of diabetic patients by enhancing blood flow, reducing inflammation, and promoting tissue regeneration. It can help prevent amputations and improve quality of life in individuals with diabetes-related complications. (2)

  1. Neurological Disorders

HBOT has been explored as a potential adjunctive therapy for various neurological conditions. Studies suggest that the increased oxygen levels delivered during HBOT can promote neuroplasticity, reduce brain inflammation, and improve brain function. This therapy may benefit patients with traumatic brain injury, stroke, multiple sclerosis, and neurodevelopmental disorders like autism. (3)

  1. Chronic Pain Management

Chronic pain is a debilitating condition that affects millions of individuals worldwide. HBOT has shown promise in alleviating chronic pain by reducing inflammation, stimulating tissue repair, and modulating pain pathways. It may provide relief for conditions such as fibromyalgia, complex regional pain syndrome, and chronic migraines. (4)

  1. Inflammatory Bowel Disease (IBD)

Inflammatory Bowel Disease, including Crohn's disease and ulcerative colitis, is characterized by chronic inflammation of the digestive tract. HBOT has shown potential in reducing inflammation, promoting tissue healing, and improving symptoms in patients with IBD. It may complement traditional therapies and enhance the overall management of these conditions. (5)

  1. Radiation Therapy Side Effects

Radiation therapy is a common treatment for cancer, but it can result in long-term side effects. HBOT has demonstrated beneficial effects in mitigating radiation-induced injuries, such as radiation cystitis, proctitis, and dermatitis. By improving tissue oxygenation, HBOT promotes healing, reduces inflammation, and enhances the recovery process. (6, 7)

Hyperbaric Oxygen Therapy (HBOT) offers a promising treatment modality for a variety of conditions, including chronic diseases. By delivering increased levels of oxygen, HBOT stimulates healing, reduces inflammation, and enhances overall tissue function. However, it is crucial to consult with integrative, naturopathic or functional medicine healthcare professionals before considering HBOT as a treatment option. While the evidence for HBOT's effectiveness in treating chronic diseases is growing, further research and clinical trials are needed to fully understand its potential and establish guidelines for its use. If you are interested in HBOT, consult with your holistic healthcare provider to determine if it may be beneficial for your specific condition.

Disclaimer: This blog post is intended for informational purposes only and should not replace professional medical advice. Always consult with a qualified holistic healthcare professional before considering any medical treatments or therapies.


  1. Růžička J, Dejmek J, Bolek L, Beneš J, Kuncová J. Hyperbaric oxygen influences chronic wound healing - a cellular level review. Physiol Res. 2021 Dec 31;70(S3):S261-S273. doi: 10.33549/physiolres.934822. PMID: 35099246; PMCID: PMC8884396.
  2. Resanović I, Zarić B, Radovanović J, Sudar-Milovanović E, Gluvić Z, Jevremović D, Isenović ER. Hyperbaric Oxygen Therapy and Vascular Complications in Diabetes Mellitus. Angiology. 2020 Nov;71(10):876-885. doi: 10.1177/0003319720936925. Epub 2020 Jul 8. PMID: 32638622.
  3. Marcinkowska AB, Mankowska ND, Kot J, Winklewski PJ. Impact of Hyperbaric Oxygen Therapy on Cognitive Functions: a Systematic Review. Neuropsychol Rev. 2022 Mar;32(1):99-126. doi: 10.1007/s11065-021-09500-9. Epub 2021 Apr 13. PMID: 33847854; PMCID: PMC8888529.
  4. Schiavo S, DeBacker J, Djaiani C, Bhatia A, Englesakis M, Katznelson R. Mechanistic Rationale and Clinical Efficacy of Hyperbaric Oxygen Therapy in Chronic Neuropathic Pain: An Evidence-Based Narrative Review. Pain Res Manag. 2021 Apr 22;2021:8817504. doi: 10.1155/2021/8817504. PMID: 33976752; PMCID: PMC8084668.
  5. Singh AK, Jha DK, Jena A, Kumar-M P, Sebastian S, Sharma V. Hyperbaric oxygen therapy in inflammatory bowel disease: a systematic review and meta-analysis. Eur J Gastroenterol Hepatol. 2021 Dec 1;33(1S Suppl 1):e564-e573. doi: 10.1097/MEG.0000000000002164. PMID: 33905214.
  6. Batenburg MCT, Maarse W, van der Leij F, Baas IO, Boonstra O, Lansdorp N, Doeksen A, van den Bongard DHJG, Verkooijen HM. The impact of hyperbaric oxygen therapy on late radiation toxicity and quality of life in breast cancer patients. Breast Cancer Res Treat. 2021 Sep;189(2):425-433. doi: 10.1007/s10549-021-06332-2. Epub 2021 Jul 19. PMID: 34279734; PMCID: PMC8357739.
  7. Villeirs L, Tailly T, Ost P, Waterloos M, Decaestecker K, Fonteyne V, Van Praet C, Lumen N. Hyperbaric oxygen therapy for radiation cystitis after pelvic radiotherapy: Systematic review of the recent literature. Int J Urol. 2020 Feb;27(2):98-107. doi: 10.1111/iju.14130. Epub 2019 Oct 15. PMID: 31617263.

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