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What Is Complex Chronic Disease?

Written by Portland Clinic of Natural Health on November 9, 2023

Complex chronic disease refers to a category of illnesses that are long-lasting and typically involve multiple organ systems. These diseases are often characterized by their complexity in both causes and management. Unlike acute diseases that are generally short-lived and often curable, complex chronic diseases usually require ongoing medical attention and can significantly impact a patient’s quality of life.

The Nature of Complex Chronic Diseases

Multifactorial Causes: Unlike diseases with a single cause, complex chronic diseases often arise from a combination of genetic, environmental, and lifestyle factors. For example, Type 2 diabetes is influenced by genetics, diet, and physical activity levels.

Multiple Organ Systems Involvement: These diseases frequently involve more than one organ system. For instance, diabetes affects blood sugar regulation (endocrine system) and can lead to complications in the heart, kidneys, and nerves.

Chronic Progression and Fluctuations: Complex chronic diseases often progress over time and may have periods of exacerbation and remission. This fluctuating nature adds to the challenge of management and requires continuous monitoring and adjustment of treatment plans.

Impact and Management

Quality of Life: The ongoing nature and complexity of these diseases can significantly impact patients' quality of life, affecting physical, mental, and social well-being.

Healthcare Utilization: Patients with complex chronic diseases often require frequent healthcare services, including specialist visits, hospitalizations, and long-term medication, which contribute to higher healthcare costs.

Personalized Management Approach: Effective management of complex chronic diseases requires a personalized approach, tailored to each patient’s unique combination of conditions and circumstances. This approach may involve a team of healthcare providers, including specialists, nurses, and dietitians.

Lifestyle Interventions: Alongside medical treatments, lifestyle interventions such as diet modification, exercise, and stress management play a crucial role in managing these diseases.

In the context of managing complex chronic diseases, licensed naturopathic physicians (NDs) are particularly well-suited due to their holistic approach to healthcare. This unique perspective is rooted in their extensive training, which emphasizes understanding and treating the patient as a whole, rather than focusing solely on isolated symptoms or diseases.

The Role of Naturopathic Physicians in Managing Complex Chronic Diseases

Holistic Approach: NDs are trained to look at the interplay between multiple organ systems and the overall well-being of the patient. This holistic view is essential in managing complex chronic diseases, where symptoms and conditions are often interconnected. By addressing the underlying causes and how different body systems interact, NDs can develop more effective treatment plans.

Individualized Treatment: Naturopathic medicine emphasizes personalized care. NDs spend considerable time with patients, understanding their unique health histories, lifestyle factors, and personal health goals. This in-depth understanding allows for the creation of tailored treatment strategies that address multiple aspects of a patient's health.

Integrative Modalities: NDs are trained in a variety of therapeutic modalities including herbal medicine, nutrition, lifestyle counseling, and physical medicine. This diverse skill set enables them to integrate conventional medical treatments with natural therapies, providing a comprehensive approach to managing complex chronic diseases.

Prevention and Education: NDs place a strong emphasis on disease prevention and health education. By educating patients on how lifestyle factors contribute to their health conditions, NDs empower individuals to take an active role in managing their health, which is particularly beneficial in the long-term management of chronic diseases.

Licensed Naturopathic Physicians and A Holistic Approach to Complex Chronic Illness

Licensed naturopathic physicians, with their holistic and individualized approach, are well-equipped to manage complex chronic diseases. Their ability to consider multiple organ systems simultaneously and to integrate various treatment modalities offers a comprehensive approach to patient care. This aligns closely with the growing recognition of the importance of personalized and holistic healthcare in managing chronic and complex health conditions.

Complex chronic diseases pose significant challenges to both individuals and healthcare systems. Understanding their multifaceted nature is crucial for effective management and improving patient outcomes. Ongoing research and advances in personalized medicine are critical in enhancing our approach to these complex conditions.


  1. Sevick MA, Trauth JM, Ling BS, Anderson RT, Piatt GA, Kilbourne AM, Goodman RM. Patients with Complex Chronic Diseases: perspectives on supporting self-management. J Gen Intern Med. 2007 Dec;22 Suppl 3(Suppl 3):438-44. doi: 10.1007/s11606-007-0316-z. PMID: 18026814; PMCID: PMC2150604.
  2. Iglesias FH, Celada CA, Navarro CB, Morales LP, Visus NA, Valverde CC, Dorado VM, Martínez Muñoz ML, Pueyo CB, Ramírez EL, Villaroel RM, Jordana NM, Bonet Simó JM; SABCOMP group. Complex Care Needs in Multiple Chronic Conditions: Population Prevalence and Characterization in Primary Care. A Study Protocol. Int J Integr Care. 2018 May 25;18(2):16. doi: 10.5334/ijic.3292. PMID: 30127700; PMCID: PMC6095050.
  3. Pierson M. A community-based solution to complex, chronic health needs. Front Health Serv Manage. 2008 Winter;25(2):15-23. PMID: 19205152.
  4. Reed ME, Huang J, Brand RJ, Neugebauer R, Graetz I, Hsu J, Ballard DW, Grant R. Patients with complex chronic conditions: Health care use and clinical events associated with access to a patient portal. PLoS One. 2019 Jun 19;14(6):e0217636. doi: 10.1371/journal.pone.0217636. PMID: 31216295; PMCID: PMC6583978.

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